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Dear Dr Griggs, please can you explain why these drugs are unsuitable for her2 positive cancers? Mine was er pos and her2 pos at biopsy but er / pr positive and her2 negative when the tumour was 3xamined after surgery having not been previously treated with herceptin. Despite this pathology i am being denied access to trials for er pos/ her2 negative cancers and am worried i will also be denied access to these drugs if i need them. I am currently awaiting a scan for possible bone mets. I am really worried that my unusual pathology results are putting me at a disadvantage at every turn for something i have no control over.

How can I tell if I am luminal a or luminal b?

Why does no one talk about the stabbing burning pain inside my breast and chest? I am starting to think the machines I have been treated on - are malfunctioning. 😓😓😓

If you have MBC are on the target drug pertuzumab/trastuzamab for life is it safe to have your hair dyed or colored? My hair feels healthy to me and I explained to my hair dresser that the drug only attacks cancer but she is hesitant. Are other patients on immune therapy type drugs successful? Are there any studies on this? I told her that it is not chemotherapy.

I am sorry for those who have issues with their hair growing back post chemo. I lost mine within 2 weeks of the start of chemo and within two weeks of stopping chemo, I had the fuzz start growing. It has all come back, within 12 months, curlier and with dark and grey highlights. ( as I call them). My hairdresser now has the job of helping me with new styles.

I'm almost 57 and I got the diagnosis just today, stage 2. I'm so terrified, I hope I can beat this

Thank you so much.

Excellent job

Thank you Dr. Griggs for providing this video on scar tissue.. i would appreciate an additional video on post mastectomy pain sydrome PMPS, along with chronic scar itching and chronic chest tightening pressure(?). i have had a bilateral mastectomy without recontruction..and have struggled with them for 14 yrs( have had extensive PT without too much success)..you may have provided videos on these issues and if you have, would you pls direct me to them.. thank you..

My mom 48 years old initially underwent a cholecystectomy for gallbladder stone removal & during the preoperative clearance, blood tests and spinal aspiration revealed a tumor of mammary origin. Turns out to be IDC stage IV that metastasized to nearby lymph nodes, single small foci in the liver and skin in the right gluteal region very small. Treatment prescribed includes: Zoladex 3.6mg (Administered today, to be repeated in a month) + Femara 2.5mg (Once daily) + and something else but I can’t recall the name. She’s concerned because she thought only chemo will help and afraid that hormonal therapy is not enough. Immunohistochemistry showed Tumor cells positive for pan-CK, CK7, E-Cadherin, focal positivity for Mammoglobin, ER (80% moderate intensity), PR (30% moderate intensity); negative for GCDFP15 and Her2 (score 0). • Ki67 PI: 20%. I’m actually a medical student but I don’t know what to say to reassure her and I need your advice. Do you think the treatment plan is good enough?

Thank you so much for this video. I was diagnosed with TNBC in April at the age of 30. My breast tumour was only 2.5cm when it was biopsied but had already spread to a lot of lymph nodes, the pectoralis muscles, and my chest wall. My surgeon was shocked at how much my cancer had spread from that small tumour, and reckoned it had happened within a very short space of time. I had to start chemotherapy with immunotherapy straight away and this week I will be halfway through chemo, round 8/16. I have my midway scans next week and I'm praying for a good response to chemo, especially as I have no idea what can be done for me surgically. I tested negative for all genetic mutations but am awaiting a final result for the TP53 gene mutation and praying that's negative as well. It has been incredibly difficult and devastating being given this diagnosis at a young age, and treatment is tough. I'm hoping I can come out the other side 🙏

You always have ⭐️⭐️OUTSTANDING ⭐️⭐️ information

Please pray for my mother she has stage 1 breast cancer ❤❤

Does tamoxifen have any impact on the results of oestrodiol testing?

Thanks for your video. I lost all my hair. It used to be straight - quite fine but I had lots of it and it grew fast. My hair started growing back when I finished chemo but it’s very curly. It’s a bit coarser but I have lots of it. Will it go back to being straight?

What about those who promised to be there and support but they never showed up😢. It is tough to realized that you can suddenly be alone more than your expectations!

My joints are stiff and ache once I am stationary . I am pain-free during an hour of exercise after which the aches and stiffness all return. ..fingers...sole....knees...elbows...neck..waist...I am only a month out of chemo. I am Trying fruits and ginger and tumeric.

I’m in sooo much pain I don’t know what to do the doctors are taking forever to help me I charged my whole life my diet my activities I can’t get any sleep no matter what I do…..it just hurts so much …

Hello, do you have a videoo for how to manage sleeping? Even when I cool down, I can't go back to sleep. This is even before taking Tamoxifen 😢

Rheumatoid arthritis can in rare cases also be a side effect.

Does the tumor grade (3 for example) determined at biopsy change the stage?

Can cancer itself cause fatigue before diagnosis or treatment?

Ugh. 7 months post chemo and my hair is barely an inch long. Nowhere near what is suggested as growth timing. It's fine, thin, you can still see through to the scalp. I'm not a happy camper about it. Haven't found a wig that looks even remotely normal on me.

But what if own doctor prescrib for antioxidant....

I don't have cancer, but I have long covid and I see ppl I know and they don't make eye contact.

Taxotere caused me to have permanent hair loss, I was never warned this was a possibility or that there was an alternative. Cold cap was not an option at the time either. By far the worst effect of the diagnosis.

Greetings Dr Griggs ! Have a question to ask , would Henna be beneficial Since its not chemical and also Cocount oil to massage with some Helrbal plant leaf ...

Super interesting and surprising!

I was diagnosed with invasive ductal carcinoma grade 1 stage 2 with 2 lymph nodes positive with micro metastases and progesterone positive her 2 negative, I just got surgery tree weeks ago but now I have to decide to do chemo or not. I’ll love if you can help me

Hi doc, thank you so much for all your videos and explanations, I have a request please and I hope you note my comments, Can you please make a video about stage three her2 positive, hormones negative breast Cancer? I find very little information out there on this type, mainly it’s triple positive, or Her2 negative and hormon positive

Thank you, dr. Griggs, for your informative medical advice regarding hair growth and regrowth after chemotherapy and hair care.

Excelente video, gracias!

Losing my hair was for me more traumatic than losing my breast. I used to have long golden shiny hair. Now, after 11months, i have fine, grey, curly hair that sticks out like ive had a shock. It is only 2 inches long. I hate the way i look and feel old and ugly. Taking letrozole isnt helping and im on that for ten years. Its relentlessly depressing.

My hair grew back quite well but about 6 months after it was fully grown I started to lose it again and it’s thinner now than after the first year after chemo.

Dr. Griggs, thank you for acknowledging there is a possibly(though low) your hair may not grow in or be very thin..unfortunately my hair grew in very very thin on top and fine in other areas..after years what hair I have is more curly..I had dark hair..now it is mousy brown with gray..I wear a wig the majority of the time..which after 14 years is still uncomfortable. I had a bilateral mastectomies without reconstruction(which in the long run was the right decision from a surgery perspective!)..the prosthetic bra and wig sometimes are sad reminders what difficult surgeries and treatments I experienced. But I also try to think about how grateful I am to be alive and well..

What about shaking, quivering of the body? I have trouble doing simple things like typing or writing without shaking and feeling like skin crawling.

Since 2 years I find my treatment,now I'm hormonal medicine letrozole,why my hair still very weak, falling down and no growing long?

It didn't bother me losing my hair. Its grown back curley. It is what it is.

I was 61 when I finished chemo. A year later I still only have about 3 inches of hair. I had long thick hair all my life. Now it is fine and breaks easy. Still falls out. Possibly bc of taking verzenio and anastrozole. Eyebrows and eyelashes are normal and unfortunately chin hairs have returned 😂but I'm unhappy with the new hair on my head. Growing very slowly and curly on one side straight on the other. My hairdresser says be patient. It might take another year. 😢 being bald was the hardest thing for me and given the choice again not sure I would do chemo. It is really traumatic for some of us.

"the body can produce extra lymphoid tissue" ? that is something i would like to know more about. Its such an amzing system.Never knew i had it , until it got 'broken' and lost a few due to cancer. Living with lymphoedema gets easier the more i learn and understand why i need to do , what i have to do , to keep swelling down and slow fibrosis.

Stage 1 breast cancer I would like to try dim add diet instead of the aromatos inhibitor letrozole because I have no thyroid and I've suffered for 20 years after they took that from me I'm in a very delicate I am now diabetic and have a pacemaker my body swells up with fluid I had no cancer in my lymph nodes I would like to know what do you think of that

Can you have vaginal discharge that is light pink on Anastrozole?

Informative as usual...

😢 omg its been 6 months i finished my chemo for her2 positive breast cancer Joint pain and nurupthay not going away Its increasing since radiotherapy and targeted therapy Hope it gets better soon

On 8-4 my Birthday I'll is the day I was told "you have Breast cancer, 20years ago! But, I have permanent issues from chemo (all the stuff they don't tell you about) I have I have very painful bones, "I now use a cane! But Dr. Thinks I should be in wheel chair but I'm not ready" I now have severe osteoporosis And Broken a few bones just by getting out of bed at night..... And we have to watch my kidneys Because I have been very near my kidney doing not so great. I have so much Titanium And screws in my body holding me together, but I'm still here! Just stay positive the entire time!

What if you have a low burden of resideual disease in a positive LN after NET (neoadjuvant endocrine therapy) or pCR after NET or NCT, do you still have to have the lymph node removed?

Dr. Griggs.. thank you for addressing this..I'm a retired social worker having worked with adults in need of financial support and insurance coverage..there are resources available.. it is essential to reach out to a social worker/financial counselors connected to your cancer center.. I think they are the best people to direct you to all the resources available covering the medical experiences I was very fortunate..I had my expenses covered by Medicare and a Supplemental Medicare insurance policy and for the cost of the HI medication, the pharmaceutical company offered a program which would cover that expense, but it is based on income eligibility.. the most important goal is to get well..

How necessary is radiation if the lymph nodes were negative and im ER+her2- im due tp start radiation in two weeks for 4 weeks then tamoxifen after that. But im a little hesitant about radiation and the tamoxifen honestly

Ps you are such a calm in the storm. Thank you thank you!

Oh boy. I am just about to start on Leterzole and read the side effects. My tests all came back that all systems are functioning fine incapacitated in any way. Have asked for Arimidex as two friends have no symptoms. Docs are discussing. Thoughts? Stage 1, hormone +, tubular C. No radiation was my choice y doc concurred as benefits are 1-5% only.